UK - Principal Scientist PKPD Non Clin

BioTalent Ltd • TRAFFIC • Berkshire, Slough, United Kingdom • 20h ago

Principal Scientist - Non-Clinical PKPD (Contract)
UK (Slough-based, VDI only - remote access provided) 12-month contract Full-time (37.5 hrs/week) £35.20-£47.92/hr (PAYE/LTD/Umbrella)

We are supporting a global biopharma organisation seeking an experienced Principal Scientist, Non-Clinical PKPD to join their Early Clinical Development & Translational Sciences group on a 12-month contract.

This role sits within the Quantitative Clinical Pharmacology function, which integrates PK/PD, systems modelling, clinical pharmacology, and DMPK approaches across the full drug development lifecycle. The position offers an excellent opportunity for a skilled pharmacokinetics/pharmacodynamics scientist to contribute to innovative drug development projects from preclinical through regulatory submission.

Key Responsibilities

Lead strategy and execution of non-clinical PKPD and GLP toxicokinetic studies.
Provide scientific input into study protocols and regulatory study designs.
Collaborate cross-functionally with Non-Clinical Safety, Bioanalysis, Clinical Pharmacology, and external CRO partners.
Ensure delivery of high-quality data packages that meet GLP and regulatory submission standards.
Analyse, interpret, and report PKPD/toxicokinetic study results; deliver reports and summaries for regulatory submissions.
Effectively communicate interim and final results to project teams and stakeholders.
Represent the function internally and externally, contributing to scientific reputation and best practices.

Candidate Profile

PhD, MSc, or BSc in pharmacology, quantitative pharmacology, pharmacokinetics/pharmacodynamics, DMPK, or related field.
5+ years' hands-on PKPD data analysis experience within pharma or CRO environments.
Strong knowledge of pharmacology and drug mechanisms.
Proven ability to design and deliver non-clinical PKPD studies and GLP toxicokinetics reports.
Proficiency with Phoenix WinNonlin is essential; experience with modelling/simulation tools (e.g., Berkeley Madonna, R) a plus.
Track record of regulatory submissions and/or scientific publications desirable.
Strong communication skills with the ability to influence and collaborate in a matrix environment.

Contract Details

Duration: 12 months (potential extension).
Hours: 37.5 per week (7.5 per day).
Location: UK-based; virtual desktop infrastructure (VDI only). Candidate provides own equipment. Future office relocation to Surrey anticipated in 2026/27.

Related Jobs

Test Manager

Experis - ManpowerGroup • TRAFFIC • Berkshire, Wokingham, United Kingdom • 20h ago

Umbrella

Test Manager 3 months Wokingham - hybrid £460 per day inside IR35 - Umbrella only SC security clearance eligible or hold active SC clearance Overview We are seeking an accomplished Test Manager & Test Strategist with...

20h ago

Apply

Tech Ops Analyst

Outsource UK lTD • TRAFFIC • Buckinghamshire, High Wycombe, United Kingdom • 1d ago

Umbrella

Job: Tech Ops Analyst Client: BAE Systems Duration: 12 months Location: Remote Hourly Rate: £31.19 PAYE, £41.94 Umbrella On-site Working Arrangements: Occasional on-site attendance in Preston Working Hours: - 37 hours pe...

1d ago

Apply

Tech Ops Analyst

Outsource UK lTD • TRAFFIC • Surrey, Guildford, United Kingdom • 1d ago

Umbrella

1d ago

Apply

Tech Ops Analyst

Outsource UK lTD • TRAFFIC • Surrey, Woking, United Kingdom • 1d ago

Umbrella

1d ago

Apply

Tech Ops Analyst

Outsource UK lTD • TRAFFIC • Hertfordshire, Hemel Hempstead, United Kingdom • 1d ago

Umbrella

1d ago

Apply

Tech Ops Analyst

Outsource UK lTD • TRAFFIC • Berkshire, Slough, United Kingdom • 1d ago

Umbrella

1d ago

Apply

Application Developer

Experis UK • London, England, GB • 1d ago

Developer Umbrella

Application Developer London - hybrid 8 Months+ Inside IR35- Umbrella only Core Technical Skills: React Native & Expo: Proficient with React Native and Expo open source modules (bare workflow) Strong React fundamenta...

1d ago

Apply

Lead Food Safety & Compliance Manager

Experis UK • Remote (London, England, GB) • 2d ago

Fully Remote Umbrella

Lead Food Safety & Compliance Manager Lead Food Safety & Compliance Manager The location of the role is Paddington, London (hybrid working) . The duration of the contract is 3 months initially. The pay rate on of...

2d ago

Apply

Front Office - Private Equity Business Analyst – eFront Specialist | London, UK

HSBC • London, England, GB • £1,000 / * • 2d ago

Business Analyst Umbrella

Job Title: Front Office - Private Equity Business Analyst – eFront Specialist Location: London (Hybrid – 2–3 days in office) Contract Type: 6-Month Contract (Strong potential for extension) Day Rate: Up to £1,000/day via...

2d ago

Apply

Programme Manager (Reinsurance experience) | London, UK | Flexible

Lorien Impellam • London, England, GB • 2d ago

Umbrella

Programme Manager (Reinsurance Experience) 6 Month Contract Via Umbrella UK Based Our Reinsurance client require a Programme Manager to help support on an exciting project for an initial 6 month contract. Key Accountabil...

2d ago

Apply

Browse Our Contract Jobs by Category

Data

238 jobs

Engineer

1566 jobs

Architect

252 jobs

Project Manager

185 jobs